Anyone know if a 15x10 wheel will fit with a 295/55r15 M/T Street S/S tire? What wheel offset do I need to run that combination?

 

A 15 x 8 needs a 5.5 Back Space

A 15 x 10 needs a 6.5 Back Spacing

But Why do you want, or think you need a 295 wide tire? You Don't!

A 275/60 or 275/50 will be plunty of tire, and fit on a 15 x 8 and fit in the wheel well.