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There is no real answer for this quesiton. The camber settings and how low you plan on going will determine if you will rub. I have a 9.5 +24 rear offset, and I can see my wheels rubbing a little possibly if I lower it too much. I think a +12 will most likely rub the fender.
Their was a thread on 350zmotoring.com of somebody running a 13 offset i think, no rubbing, but he wasn't lowerd much or not lowered at all if i remember.
unlikely.....mine are 18x9.5 with a +20 and no rubbing at all (my car is very low), with a 275/40 T1S but any bigger and I'd be shaving the fender lips