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Really depends on many factors. Is there forced induction on the car already? In most cases, you are R/R'ing engine and taking everything apart except for the shortblock and trans bell housing. That is quite a bit of work.
Since you will need to remove 90% of your twin turbo kit, you're looking at a pretty time consuming swap. Best way to go would be to drop the motor/trans out the bottom and disassemble everything outside of the car.